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Showing posts with label genome. Show all posts
Showing posts with label genome. Show all posts

Monday, July 31, 2017

DNA of Ancient Canaanites: Levant, Lebanon, and Lines


      Researchers have deciphered the complete DNA of five Canaanite skeletons. By comparing these five Canaanite genomes with those of other ancient and modern populations, the scientists identified the Canaanites’ ancestors and discovered their descendants were modern Lebanese people.




     The results, reported July 27 in the American Journal of Human Genetics, give new insight into the origins and fate of a people whose story has largely been told through the secondhand accounts of its contemporaries.




     "The Canaanites emerged in the Levant, a region east of the Mediterranean Sea, 3,000 to 4,000 years ago. This cultural group, which established extensive trade networks and colonies across the Mediterranean region, left behind few written records, perhaps because they wrote on papyrus rather than clay. So most knowledge of the Canaanites comes from ancient Egyptian, Hebrew and Greek documents."



     "But, doubt surrounds some of those accounts. For one thing, Greek historians thought the Canaanites originated near the Persian Gulf, whereas archaeological records suggest they arose from farming communities that settled the Levant up to 10,000 years ago. For another, the Old Testament makes reference to the destruction of Canaanite communities, but some of their cities, such as Sidon in Lebanon, appear to have been continually inhabited through the present day."




      
     "Researchers reconstructed the genomes of the 3,700-year-old remains of five Canaanites unearthed in Sidon. Comparisons of these genomes with those of other ancient Eurasian peoples indicate that Canaanite ancestry was split roughly 50-50 between the early farmers who settled the Levant and immigrants of Iranian descent who arrived later, between 6,600 and 3,550 years ago."




     “You’d need a lot of migration for roughly half of the population to be replaced by the incoming Iranian-related populations,” says Iosif Lazaridis, a geneticist at Harvard Medical School who was not involved in the study. “This must have been some important event in the history of the Near East.” One possibility is the spread of the Akkadian Empire, which controlled a region spanning from the Levant to Iran between 4,400 and 4,200 years ago. That connection may have presented the opportunity for interbreeding between these far-flung populations."




     "The researchers also determined that modern Lebanese people can attribute about 93 percent of their ancestry to the Canaanites. The other 7 percent comes from Eurasians who probably arrived in the Levant 3,700 to 2,200 years ago. Study coauthor Chris Tyler-Smith, was surprised by how much Canaanite heritage dominated modern Lebanese DNA. He says he expected to see a more mixed gene pool because so many populations have crossed through the Levant in the last few thousand years."





     "This study alone may not paint the complete picture of the Canaanite lineage, says Aaron Burke, an archaeologist at UCLA, because the researchers examined the genomes of only five Canaanites."



      "However, the study’s Canaanite genetic data do provide “a snapshot of history in the area,” Lazaridis said. Identifying which populations crop up in the Canaanite lineage — and when — can help trace the historical movements of people throughout the Near East. With DNA analyses of enough ancient people, Lazaridis says, “I think it will be possible to reconstruct the whole timeline of what happened in Lebanon and other parts of the world.” 

No lamentations; looking forward to more data!
Steph

Monday, July 14, 2014

Your Genetic Constitution, My Genetic Constitution: Friends Sharing DNA

     

     The company you keep may include similar genetic material--up to 1 percent shared DNA amongst your friends--according to a new study from scientists at the University of California--San Diego and Yale University published in the Proceedings of the National Academy of Sciences.





     "Looking across the whole genome," co-author James Fowler said, "we find that, on average, we are genetically similar to our friends. We have more DNA in common with the people we pick as friends than we do with strangers in the same population."




     The researchers focused on 1,932 subjects from the Framingham Heart study; they compared pairs of unrelated friends against pairs of unrelated strangers. The same people, who were neither biologically related nor spouses, were used in both types of samples. The only thing that differed between them was their social relationship.
 
   The study controlled for ancestry (see study link below) and is a genome-wide analysis of nearly 1.5 million markers of gene variation. The researchers concluded that friends have similar genetic material to 4th cousins and that the shared genetic material is statistically significant.

    The strongest correlation between friends was sense of smell and the least correlated was resistance to diseases.

     The study is described in the 7-14-14 edition of Science Daily:

GENOME ANALYSIS AMONG FRIENDS

     So, mes amis, what are your favorite smells?! Least favorite smells? Do you suppose the study would be valid for on-line friends?

      My favorites smells are petriclor, lilacs, lemon, coffee, newly mown grass, pine trees, cinnamon, and baby-head smell. Least favorites? Mold, old sour milk, and ammonia.


      

      The paper also lends support to the view of human beings as 'metagenomic,'" co-author Nicholas Christakis said, "not only with respect to the microbes within us but also to the people who surround us. It seems that our fitness depends not only on our own genetic constitutions, but also on the genetic constitutions of our friends."
 
      So how's your genome profile? We all depend on each other, after all. . .







     And lastly, this misspelling of Quatorze de Juillet was too good to pass up. Happy Bastille Day, Julliet, Juliette, Julius, et al! 




Vive mes amis,

Steph
(Femme des Mots)

Any guesses as to what these are?